Genotoxic effects of aluminum, iron and manganese in human ...
· Exposures to high levels of manganese by ingestion or inhalation can damage the central nervous system. 38 High doses (1800–2250 mg/kg/day as manganese (II) sulfate) in mice induce hyperplasia, erosion and inflammation in the stomach. 39 Chronic exposure to high levels of Mn can also induce a syndrome known as manganism, characterized by extrapyramidal dysfunction (bradykinesia, .
